| ชื่อโครงการวิจัย/ชื่อเรื่อง | Use of a combination of ketamine and dexmedetomidine (Ketodex) in different clinical cases |
|---|---|
| ชื่อนักวิจัย/ชื่อผู้แต่ง | Somchai Amornyotin |
| คำสำคัญ | Ketamine;Dexmedetomidine;Clinical use;Efficacy;Safety |
| ปีที่เผยแพร่ | 2564 |
| คำอธิบาย | Ketodex is a combination of ketamine and dexmedetomidine. Ketamine, an old intravenous anesthetic, is a non-narcotic and non-barbiturate drug. It has several properties of the ideal anesthetic agent. However, ketamine can produce the psychological adverse effects. Dexmedetomidine has analgesic, amnesic, sedative and anxiolytic properties. A distinct advantage of dexmedetomidine is the maintenance of respiratory force and preserved airway patency. It converges on a natural sleep pathway, activating pathways that promote endogenous non-rapid eye movement sleep to exert its sedative effect. However, dexmedetomidine can produce bradycardia and hypotension. A combination of ketamine and dexmedetomidine has several benefi ts in the terms of hemodynamic stability, absence of respiratory depression, post-operative analgesia and recovery. Several previous studies have been demonstrated the therapeutic utility of the combination of ketamine and dexmedetomidine. |
| ข้อมูลเพิ่มเติม | https://dx.doi.org/10.17352/2455-3484.000036 |
| สาขาการวิจัย |
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Use of a combination of ketamine and dexmedetomidine (Ketodex) in different clinical cases is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 Thailand License.
